Proteomic response to amino acid starvation in Candida albicans and Saccharomyces cerevisiae
Ontology highlight
ABSTRACT:
INSTRUMENT(S): instrument model
ORGANISM(S): Candida Albicans (yeast) Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: 
DAVE THORNEYCROFT
PROVIDER: PRD000762 | Pride | 2007-05-04
REPOSITORIES: Pride
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Publications
Proteomic response to amino acid starvation in Candida albicans and Saccharomyces cerevisiae.
Yin Zhikang Z Stead David D Selway Laura L Walker Janet J Riba-Garcia Isabel I McLnerney Tracey T Gaskell Simon S Oliver Stephen G SG Cash Philip P Brown Alistair J P AJ
Proteomics 20040801 8
Saccharomyces cerevisiae activates general amino acid control (GCN) in response to amino acid starvation. Some aspects of this response are known to be conserved in other fungi including Candida albicans, the major systemic fungal pathogen of humans. Here, we describe a proteomic comparison of the GCN responses in S. cerevisiae and C. albicans. We have used high-resolution two-dimensional (2-D) gel electrophoresis and peptide mass fingerprinting to develop a 2-D protein map of C. albicans. A tot ...[more]
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