Proteomics

Dataset Information

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Proteomics characterization of the ram and rat testicular fluid


ABSTRACT: Proteomics characterization of the ram and rat testicular fluid

INSTRUMENT(S): LTQ Orbitrap, instrument model

ORGANISM(S): Rattus Norvegicus (rat) Ovis Aries

TISSUE(S): Testis

SUBMITTER: E Com  

PROVIDER: PRD000847 | Pride | 2014-08-29

REPOSITORIES: Pride

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Publications

An integrative omics strategy to assess the germ cell secretome and to decipher sertoli-germ cell crosstalk in the Mammalian testis.

Chalmel Frédéric F   Com Emmanuelle E   Lavigne Régis R   Hernio Nolwen N   Teixeira-Gomes Ana-Paula AP   Dacheux Jean-Louis JL   Pineau Charles C  

PloS one 20140811 8


Mammalian spermatogenesis, which takes place in complex testicular structures called seminiferous tubules, is a highly specialized process controlled by the integration of juxtacrine, paracrine and endocrine information. Within the seminiferous tubules, the germ cells and Sertoli cells are surrounded by testicular fluid (TF), which probably contains most of the secreted proteins involved in crosstalk between these cells. It has already been established that germ cells can modulate somatic Sertol  ...[more]

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