Purified FLAG-Hrp1 GeLC-MS/MS - CHD1 remodelers regulate nucleosome spacing in vitro and align nucleosomal arrays over gene coding regions in S
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA177319
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Schizosaccharomyces Pombe
SUBMITTER: 
Rui Branca
PROVIDER: PXD000031 | Pride | 2012-11-01
REPOSITORIES: Pride
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Publications
CHD1 remodelers regulate nucleosome spacing in vitro and align nucleosomal arrays over gene coding regions in S. pombe.
Pointner Julia J Persson Jenna J Prasad Punit P Norman-Axelsson Ulrika U Strålfors Annelie A Khorosjutina Olga O Krietenstein Nils N Svensson J Peter JP Ekwall Karl K Korber Philipp P
The EMBO journal 20121026 23
Nucleosome positioning governs access to eukaryotic genomes. Many genes show a stereotypic organisation at their 5'end: a nucleosome free region just upstream of the transcription start site (TSS) followed by a regular nucleosomal array over the coding region. The determinants for this pattern are unclear, but nucleosome remodelers are likely critical. Here we study the role of remodelers in global nucleosome positioning in S. pombe and the corresponding changes in expression. We find a striking ...[more]
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