A multi-omic analysis of an Enterococcus faecium mutant reveals genetic mutation and dramatic changes of mRNA and protein expressions
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ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Enterococcus Faecalis (streptococcus Faecalis)
SUBMITTER: 
Liu liu
PROVIDER: PXD000326 | Pride | 2014-04-16
REPOSITORIES: Pride
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A multi-omic analysis of an Enterococcus faecium mutant reveals specific genetic mutations and dramatic changes in mRNA and protein expression.
Chang De D Zhu Yuanfang Y An Li L Liu Jinwen J Su Longxiang L Guo Yinghua Y Chen Zhenhong Z Wang Yajuan Y Wang Li L Wang Junfeng J Li Tianzhi T Fang Xiangqun X Fang Chengxiang C Yang Ruifu R Liu Changting C
BMC microbiology 20131228
<h4>Background</h4>For a long time, Enterococcus faecium was considered a harmless commensal of the mammalian gastrointestinal (GI) tract and was used as a probiotic in fermented foods. In recent decades, E. faecium has been recognised as an opportunistic pathogen that causes diseases such as neonatal meningitis, urinary tract infections, bacteremia, bacterial endocarditis and diverticulitis. E. faecium could be taken into space with astronauts and exposed to the space environment. Thus, it is n ...[more]
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