Proteomics

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Combined Proteomic and Transcriptomic Interrogation of the Venom Gland of Conus geographus


ABSTRACT: Combined Proteomic and Transcriptomic Interrogation of the Venom Gland of Conus geographus Uncovers Novel Components and Functional Compartmentalization

INSTRUMENT(S): ultraflex III TOF/TOF

ORGANISM(S): Conus Geographus (geography Cone) (nubecula Geographus)

TISSUE(S): Venom Gland

SUBMITTER: Paul Veith  

LAB HEAD: Paul Veith

PROVIDER: PXD000581 | Pride | 2014-07-28

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
A2_Part2_Spot_101.zip Other
A2_Part2_Spot_102.zip Other
A2_Part2_Spot_107.zip Other
A2_Part2_Spot_109.zip Other
A2_Part2_Spot_11.zip Other
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Publications

Combined proteomic and transcriptomic interrogation of the venom gland of Conus geographus uncovers novel components and functional compartmentalization.

Safavi-Hemami Helena H   Hu Hao H   Gorasia Dhana G DG   Bandyopadhyay Pradip K PK   Veith Paul D PD   Young Neil D ND   Reynolds Eric C EC   Yandell Mark M   Olivera Baldomero M BM   Purcell Anthony W AW  

Molecular & cellular proteomics : MCP 20140129 4


Cone snails are highly successful marine predators that use complex venoms to capture prey. At any given time, hundreds of toxins (conotoxins) are synthesized in the secretory epithelial cells of the venom gland, a long and convoluted organ that can measure 4 times the length of the snail's body. In recent years a number of studies have begun to unveil the transcriptomic, proteomic and peptidomic complexity of the venom and venom glands of a number of cone snail species. By using a combination o  ...[more]

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