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Bacillus subtilis under Curcumin treatment LC-MS/MS

ABSTRACT: Comprehensive Analysis of Temporal Alterations in Cellular Proteome of Bacillus subtilis under Curcumin Treatment

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Bacillus Subtilis Subsp. Subtilis Str. 168

TISSUE(S): Fat Body

SUBMITTER: sanjeeva Srivastava

LAB HEAD: Sanjeeva Srivastava

PROVIDER: PXD000644 | Pride | 2019-11-20

REPOSITORIES: Pride

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			Action	DRS
	Bacillus_Curcumin_TP_10.raw	Raw
	Bacillus_Curcumin_TP_11.raw	Raw
	Bacillus_Curcumin_TP_12.raw	Raw
	Bacillus_Curcumin_TP_13.raw	Raw
	Bacillus_Curcumin_TP_15.raw	Raw

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Publications

Comprehensive analysis of temporal alterations in cellular proteome of Bacillus subtilis under curcumin treatment.

Reddy Panga Jaipal PJ Sinha Sneha S Ray Sandipan S Sathe Gajanan J GJ Chatterjee Aditi A Prasad T S Keshava TS Dhali Snigdha S Srikanth Rapole R Panda Dulal D Srivastava Sanjeeva S

PloS one 20150414 4

Curcumin is a natural dietary compound with antimicrobial activity against various gram positive and negative bacteria. This study aims to investigate the proteome level alterations in Bacillus subtilis due to curcumin treatment and identification of its molecular/cellular targets to understand the mechanism of action. We have performed a comprehensive proteomic analysis of B. subtilis AH75 strain at different time intervals of curcumin treatment (20, 60 and 120 min after the drug exposure, thre ...[more]

PMID: 25874956

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