Dataset Information

Caudate nucleus proteome - Anatomo-proteomic characterization of human basal ganglia: focus on striatum and globus pallidus

ABSTRACT: In order to analyse thecaudate nucleus proteome in a large-scale format, we used a multi-dimensional fractionation approach which combines isolation of anatomically-defined nuclei, and protein/peptide chromatographic fractionation strategies coupled to mass spectrometry.

INSTRUMENT(S): Q TRAP

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

DISEASE(S): Disease Free

SUBMITTER: Enrique SantamarÃa

LAB HEAD: Enrique Santamaria

PROVIDER: PXD000742 | Pride | 2018-10-19

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	CaudadoA10_1171220127.wiff	Wiff
	CaudadoA10_2171220128.wiff	Wiff
	CaudadoA11_1171220129.wiff	Wiff
	CaudadoA11_21712201210.wiff	Wiff
	CaudadoA12_11712201211.wiff	Wiff

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Anatomo-proteomic characterization of human basal ganglia: focus on striatum and globus pallidus.

Fernández-Irigoyen Joaquín J Zelaya María Victoria MV Tuñon Teresa T Santamaría Enrique E

Molecular brain 20141118

<h4>Background</h4>The basal ganglia (BG) are a complex network of subcortical nuclei involved in the coordination and integration of the motor activity. Although these independent anatomical structures are functionally related, the proteome present in each isolated nucleus remains largely unexplored. In order to analyse the BG proteome in a large-scale format, we used a multi-dimensional fractionation approach which combines isolation of anatomically-defined nuclei, and protein/peptide chromato ...[more]

PMID: 25406675

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