Proteomics

Dataset Information

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Bacillus cereus proteomics - Proteomic evidences for rex regulation of metabolism in toxin-producing Bacillus cereus ATCC 14579

ABSTRACT: This project contributes to the proteomic comparison of Bacillus cereus wild-type and Bacillus cereus mutant devoided of the Rex regulator. Aerobiosis and anaerobiosis conditions were assayed.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Bacillus Cereus (strain Atcc 14579 / Dsm 31)

SUBMITTER: Jean ARMENGAUD  

LAB HEAD: Armengaud

PROVIDER: PXD000856 | Pride | 2016-07-09

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
BCRUS01_20081203b.fasta Fasta
F059500.dat-pride-filtered.pride.mgf.gz Mgf
F059500.dat-pride-filtered.pride.mztab.gz Mztab
F059500.dat-pride-filtered.xml.gz Xml
F059501.dat-pride-filtered.pride.mgf.gz Mgf
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Publications

Proteomic evidences for rex regulation of metabolism in toxin-producing Bacillus cereus ATCC 14579.

Laouami Sabrina S   Clair Géremy G   Armengaud Jean J   Duport Catherine C  

PloS one 20140912 9

The facultative anaerobe, Bacillus cereus, causes diarrheal diseases in humans. Its ability to deal with oxygen availability is recognized to be critical for pathogenesis. The B. cereus genome comprises a gene encoding a protein with high similarities to the redox regulator, Rex, which is a central regulator of anaerobic metabolism in Bacillus subtilis and other Gram-positive bacteria. Here, we showed that B. cereus rex is monocistronic and down-regulated in the absence of oxygen. The protein en  ...[more]