Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Eye
SUBMITTER: Guy Uechi
LAB HEAD: Guy T. Uechi
PROVIDER: PXD001025 | Pride | 2014-07-16
REPOSITORIES: Pride
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Uechi Guy G Sun Zhiyuan Z Schreiber Emanuel M EM Halfter Willi W Balasubramani Manimalha M
Journal of proteome research 20140717 8
Basement membranes (BMs) are extracellular matrix sheets comprising the laminins, type-IV collagens, nidogens, and the heparan sulfate proteoglycans, perlecan, collagen XVIII, and agrin. In intact BMs, BM proteins are physiologically insoluble and partially resistant to proteolytic digestion, making BMs a challenge to study. Here three types of BMs from adult human eyes, the inner limiting membrane (ILM), the retinal vascular BMs, and the lens capsule, were isolated for analysis by 1D-SDS-PAGE a ...[more]