Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA245859
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Permanent Cell Line Cell
DISEASE(S): Neuroblastoma
SUBMITTER: Alex von kriegsheim
LAB HEAD: Alex von Kriegsheim
PROVIDER: PXD001070 | Pride | 2015-04-17
REPOSITORIES: Pride
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130514_G_GFP1_140516123228.raw | Raw | |||
130514_G_GFP1_140516155450.raw | Raw | |||
130514_G_GFP2.raw | Raw |
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Molecular and cellular biology 20150330 11
Neurons exploit local mRNA translation and retrograde transport of transcription factors to regulate gene expression in response to signaling events at distal neuronal ends. Whether epigenetic factors could also be involved in such regulation is not known. We report that the mRNA encoding the high-mobility group N5 (HMGN5) chromatin binding protein localizes to growth cones of both neuron-like cells and of hippocampal neurons, where it has the potential to be translated, and that HMGN5 can be re ...[more]