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Proteomic profiles in Acute Respiratory Distress Syndrome differentiates

ABSTRACT: Bronchoalveolar Lavage Fluid protein profile was characterized in ARDS subjects. Patients were divided into three groups: 1) Early phase survivors 2) Early phase non-survivors and 3) Late phase survivors. Bronchoalveolar lavage fluid was pooled within each group for sample preparation and mass spectrometry

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Pneumocyte, Bronchoalveolar Lavage

DISEASE(S): Adult Respiratory Distress Syndrome

SUBMITTER: Maneesh Bhargava

LAB HEAD: Maneesh Bhargava

PROVIDER: PXD001095 | Pride | 2016-07-07

REPOSITORIES: Pride

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			Action	DRS
	Galaxy55-PROTEIN_report_for_data_52.tabular.txt	Txt
	bharg005_becke513_100812_12202_iTQ3_11_26.raw	Raw
	bharg005_becke513_100812_12202_iTQ3_12_27.raw	Raw
	bharg005_becke513_100812_12202_iTQ3_13_28.raw	Raw
	bharg005_becke513_100812_12202_iTQ3_14_29.raw	Raw

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Publications

Proteomic profiles in acute respiratory distress syndrome differentiates survivors from non-survivors.

Bhargava Maneesh M Becker Trisha L TL Viken Kevin J KJ Jagtap Pratik D PD Dey Sanjoy S Steinbach Michael S MS Wu Baolin B Kumar Vipin V Bitterman Peter B PB Ingbar David H DH Wendt Christine H CH

PloS one 20141007 10

Acute Respiratory Distress Syndrome (ARDS) continues to have a high mortality. Currently, there are no biomarkers that provide reliable prognostic information to guide clinical management or stratify risk among clinical trial participants. The objective of this study was to probe the bronchoalveolar lavage fluid (BALF) proteome to identify proteins that differentiate survivors from non-survivors of ARDS. Patients were divided into early-phase (1 to 7 days) and late-phase (8 to 35 days) groups ba ...[more]

PMID: 25290099

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