Dataset Information
Proteomic analysis of B16-MDSCs
Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture, Myeloid Suppressor Cell
DISEASE(S): Melanoma
SUBMITTER: 
Enrique SantamarÃa
LAB HEAD: Enrique Santamaria
PROVIDER: PXD001103 | Pride | 2016-07-07
REPOSITORIES: Pride
Dataset's files
Items per page: 1 - 5 of 16 |
Publications
A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice.
Oncotarget 20140901 17
Myeloid-derived suppressor cells (MDSCs) exhibit potent immunosuppressive activities in cancer. MDSCs infiltrate tumors and strongly inhibit cancer-specific cytotoxic T cells. Their mechanism of differentiation and identification of MDSC-specific therapeutic targets are major areas of interest. We have devised a highly efficient and rapid method to produce very large numbers of melanoma-infiltrating MDSCs ex vivo without inducing tumors in mice. These MDSCs were used to study their differentiati ...[more]
