Dataset Information
Integrative Genomics Positions MKRN1 as a Novel Ribonucleoprotein within the Embryonic Stem Cell Gene Regulatory Network
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: GSE59394PRJNA255236PRJNA255235PRJNA255234
INSTRUMENT(S): LTQ
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Embryonic Stem Cell
SUBMITTER: 
Gareth Palidwor
LAB HEAD: Dr. William Stanford
PROVIDER: PXD001191 | Pride | 2018-10-19
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Exp1_FLAG_Ctrl-MG132_IP577.RAW | Raw | |||
| Exp1_FLAG_CtrlMG132_IP581.RAW | Raw | |||
| Exp1_FLAG_MKRN1-MG132_IP572.RAW | Raw | |||
| Exp1_FLAG_MKRN1D5-MG132_IP583.RAW | Raw | |||
| Exp1_FLAG_MKRN1D5MG132_IP584.RAW | Raw |
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Publications
Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.
EMBO reports 20150811 10
In embryonic stem cells (ESCs), gene regulatory networks (GRNs) coordinate gene expression to maintain ESC identity; however, the complete repertoire of factors regulating the ESC state is not fully understood. Our previous temporal microarray analysis of ESC commitment identified the E3 ubiquitin ligase protein Makorin-1 (MKRN1) as a potential novel component of the ESC GRN. Here, using multilayered systems-level analyses, we compiled a MKRN1-centered interactome in undifferentiated ESCs at the ...[more]
