Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brain
SUBMITTER: Kelly Stauch
LAB HEAD: Howard Fox
PROVIDER: PXD001370 | Pride | 2015-01-27
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 84 |
Stauch Kelly L KL Purnell Phillip R PR Villeneuve Lance M LM Fox Howard S HS
Proteomics 20150210 9
Mitochondria are the main cellular source of reactive oxygen species and are recognized as key players in several age-associated disorders and neurodegeneration. Their dysfunction has also been linked to cellular aging. Additionally, mechanisms leading to the preservation of mitochondrial function promote longevity. In this study we investigated the proteomic and functional alterations in brain mitochondria isolated from mature (5 months old), old (12 months old), and aged (24 months old) mice a ...[more]