Dataset Information

Proteome profiling of ovarian cancer and cirrhosis ascites

ABSTRACT: Proteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication http://www.mcponline.org/content/early/2014/09/30/mcp.M114.041194.full.pdf+html?sid=78e7a955-fa54-4ded-b296-89f1fb6adbec

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Ascites

DISEASE(S): Liver Cirrhosis,Malignant Neoplasm Of Ovary

SUBMITTER: Georgij Arapidi

LAB HEAD: Georgij Arapidi

PROVIDER: PXD001403 | Pride | 2014-10-23

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	Ascit_OvC-CIR_Alignment-noAlignment_FinalResults_2.1_frozen.sf3	Other
	V014-V017.2013_05_15_17_28_21.t.XML	Xml
	V014-V017.2013_05_15_17_28_21.t.XML.mzid.gz	Mzid
	V014-V017.2013_05_15_17_28_21.t.XML.mzid_V014-V017.2013_05_15_17_28_21.t.XML.MGF	Mzid
	V014-V017.2013_05_15_17_28_21.t.XML.mzid_V014-V017.2013_05_15_17_28_21.t.XML.pride.mgf.gz	Mzid

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Publications

Proteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication.

Shender Victoria O VO Pavlyukov Marat S MS Ziganshin Rustam H RH Arapidi Georgij P GP Kovalchuk Sergey I SI Anikanov Nikolay A NA Altukhov Ilya A IA Alexeev Dmitry G DG Butenko Ivan O IO Shavarda Alexey L AL Khomyakova Elena B EB Evtushenko Evgeniy E Ashrafyan Lev A LA Antonova Irina B IB Kuznetcov Igor N IN Gorbachev Alexey Yu AY Shakhparonov Mikhail I MI Govorun Vadim M VM

Molecular & cellular proteomics : MCP 20140930 12

Ovarian cancer ascites is a native medium for cancer cells that allows investigation of their secretome in a natural environment. This medium is of interest as a promising source of potential biomarkers, and also as a medium for cell-cell communication. The aim of this study was to elucidate specific features of the malignant ascites metabolome and proteome. In order to omit components of the systemic response to ascites formation, we compared malignant ascites with cirrhosis ascites. Metabolome ...[more]

PMID: 25271300

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