Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Rachel Li
LAB HEAD: Hyung Won Choi
PROVIDER: PXD001426 | Pride | 2015-06-29
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
2014_01_HUMAN.fasta | Fasta | |||
MaxQuantOutput.tar.gz | Other | |||
QE_140221_01_UPS1_100fmolspiked.mgf | Mgf | |||
QE_140221_01_UPS1_100fmolspiked.raw | Raw | |||
QE_140221_02_UPS1_300fmolspiked.mgf | Mgf |
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Proteomics 20150528 15
Labeling-based proteomics is a powerful method for detection of differentially expressed proteins (DEPs). The current data analysis platform typically relies on protein-level ratios, which is obtained by summarizing peptide-level ratios for each protein. In shotgun proteomics, however, some proteins are quantified with more peptides than others, and this reproducibility information is not incorporated into the differential expression (DE) analysis. Here, we propose a novel probabilistic framewor ...[more]