Dataset Information

T. pseudoethanolicus response to furfural stress - LC-MS/MS

ABSTRACT: Identification of the furfural detoxifying machinery in T. pseudoethanolicus (Tps) by LC-MS/MS based proteomics for engineering cellulolytic microbes involved in bioethanol production.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Thermoanaerobacter Pseudethanolicus

SUBMITTER: Richard J. Giannone

LAB HEAD: Richard J. Giannone

PROVIDER: PXD001446 | Pride | 2018-10-19

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	20110804_Tps_Furfural-_Bio1_Run1_100ug_LTQ3_02.mzML	Mzml
	20110804_Tps_Furfural-_Bio1_Run1_100ug_LTQ3_03.mzML	Mzml
	20110804_Tps_Furfural-_Bio1_Run1_100ug_LTQ3_04.mzML	Mzml
	20110804_Tps_Furfural-_Bio1_Run1_100ug_LTQ3_05.mzML	Mzml
	20110804_Tps_Furfural-_Bio1_Run1_100ug_LTQ3_06.mzML	Mzml

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Publications

A comparative multidimensional LC-MS proteomic analysis reveals mechanisms for furan aldehyde detoxification in Thermoanaerobacter pseudethanolicus 39E.

Clarkson Sonya M SM Hamilton-Brehm Scott D SD Giannone Richard J RJ Engle Nancy L NL Tschaplinski Timothy J TJ Hettich Robert L RL Elkins James G JG

Biotechnology for biofuels 20141203 1

<h4>Background</h4>Chemical and physical pretreatment of lignocellulosic biomass improves substrate reactivity for increased microbial biofuel production, but also restricts growth via the release of furan aldehydes, such as furfural and 5-hydroxymethylfurfural (5-HMF). The physiological effects of these inhibitors on thermophilic, fermentative bacteria are important to understand; especially as cellulolytic strains are being developed for consolidated bioprocessing (CBP) of lignocellulosic feed ...[more]

PMID: 25506391

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