Proteomics

Dataset Information

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Multi-organ proteomics of rhesus macaque for prototype proteome bank of non–human primate


ABSTRACT: Though the rhesus monkey is one of the most valuable non-human primate animal models for various human diseases because of its manageable size and genetic and proteomic similarities with humans, proteomic research using rhesus monkeys still remains challenging due to the lack of a complete protein sequence database and sufficient proteomic information. In this project, proteomic profiling of multiple organ tissues, 9 male and 11 female were performed in an automated, high-throughput manner employing annotated UniProtKB human database. Based on the success of this alternative interpretation of MS data, the list of proteins identified from total 12 organs of male and female subjects will benefit future rhesus monkey proteome research.

INSTRUMENT(S): LTQ

ORGANISM(S): Macaca Mulatta (rhesus Macaque)

TISSUE(S): Spleen, Cerebellum, Ovary, Prostate Gland, Clitoris, Frontal Lobe, Penis, Liver, Breast, Pancreas

SUBMITTER: Sunil Hwang  

LAB HEAD: Sunil Hwang

PROVIDER: PXD001972 | Pride | 2015-05-19

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
FEMALE_BREAST2_1.RAW Raw
FEMALE_BREAST2_10.RAW Raw
FEMALE_BREAST2_11.RAW Raw
FEMALE_BREAST2_12.RAW Raw
FEMALE_BREAST2_13.RAW Raw
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Though the rhesus monkey is one of the most valuable non-human primate animal models for various human diseases because of its manageable size and genetic and proteomic similarities with humans, proteomic research using rhesus monkeys still remains challenging due to the lack of a complete protein sequence database and effective strategy. To investigate the most effective and high-throughput proteomic strategy, comparative data analysis was performed employing various protein databases and searc  ...[more]

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