Proteomics

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Social interaction dependent protein expression dynamics in hippocampus of the animals with strong features of dominance and submissiveness


ABSTRACT: Social interaction dependent protein expression dynamics in hippocampus of the animals with strong features of dominance and submissiveness.

INSTRUMENT(S): Synapt MS

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain, Hippocampus

SUBMITTER: Yishai Levin  

LAB HEAD: Izhak Michaelevsky

PROVIDER: PXD002118 | Pride | 2017-07-11

REPOSITORIES: Pride

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Publications

Effect of social interactions on hippocampal protein expression in animal dominant and submissive model of behavioral disorders.

Borovok Natalia N   Nesher Elimelech E   Reichenstein Michal M   Tikhonova Tatiana T   Levin Yishai Y   Pinhasov Albert A   Michaelevski Izhak I  

Proteomics. Clinical applications 20170927 11-12


<h4>Purpose</h4>Psychiatric conditions, in many cases, arise from social interactions necessary for optimal mental functioning. Dominance and submissiveness are two opposite poles of behavior, stemming from processes of social interactions between members inside one group or species. Extreme dominance and submissiveness expressions in humans is accompanied by mental impairments, including mania and depression. Here, taking advantage of animals bred selectively for traits of dominance and submiss  ...[more]

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