RDEB Mouse Model - Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms

ABSTRACT: Expression proteomics of back skin of collagen VII (C7) hypomorphic and WT mice was performed to detect differences in the skin proteome dependent on the presence of collagen VII and the treatment with losartan.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Keratinocyte, Skin, Fibroblast

DISEASE(S): Epidermolysis Bullosa

SUBMITTER: Joern Dengjel  

LAB HEAD: Joern Dengjel

PROVIDER: PXD002134 | Pride | 2015-10-02

REPOSITORIES: Pride