Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Drosophila Melanogaster (fruit Fly)
TISSUE(S): Whole Body
SUBMITTER: Andrew James
LAB HEAD: Michael Patrick Murphy
PROVIDER: PXD002195 | Pride | 2018-10-24
REPOSITORIES: Pride
Action | DRS | |||
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CatalaseOverexControl.zip | Other | |||
CatalaseOverexH2O2.zip | Other | |||
CatalaseOverexPQ.zip | Other | |||
CatalaseOverexStarve.zip | Other | |||
SupplementalTable1.zip | Other |
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Menger Katja E KE James Andrew M AM Cochemé Helena M HM Harbour Michael E ME Chouchani Edward T ET Ding Shujing S Fearnley Ian M IM Partridge Linda L Murphy Michael P MP
Cell reports 20150618 12
Altering the redox state of cysteine residues on protein surfaces is an important response to environmental challenges. Although aging and fasting alter many redox processes, the role of cysteine residues is uncertain. To address this, we used a redox proteomic technique, oxidative isotope-coded affinity tags (OxICAT), to assess cysteine-residue redox changes in Drosophila melanogaster during aging and fasting. This approach enabled us to simultaneously identify and quantify the redox state of s ...[more]