Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human) Escherichia Coli Saccharomyces Cerevisiae (baker's Yeast) Mus Musculus (mouse)
TISSUE(S): Liver
SUBMITTER: Brian Weinert
LAB HEAD: Brian Weinert, Chunaram Choudhary
PROVIDER: PXD002277 | Pride | 2015-06-02
REPOSITORIES: Pride
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Cell reports 20130815 4
Recent studies have shown that lysines can be posttranslationally modified by various types of acylations. However, except for acetylation, very little is known about their scope and cellular distribution. We mapped thousands of succinylation sites in bacteria (E. coli), yeast (S. cerevisiae), human (HeLa) cells, and mouse liver tissue, demonstrating widespread succinylation in diverse organisms. A majority of succinylation sites in bacteria, yeast, and mouse liver were acetylated at the same po ...[more]