Proteomics

Dataset Information

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Panorama of ancient metazoan macromolecular complexes: Saccharomyces cerevisiae

ABSTRACT: By combining extensive biochemical fractionation with quantitative mass spectrometry, we directly examined the composition of soluble multiprotein complexes among diverse animal models. The project has been jointly supervised by Andrew Emili and Edward M. Marcotte. Project website: http://metazoa.med.utoronto.ca

INSTRUMENT(S): LTQ Orbitrap Velos, LTQ XL

ORGANISM(S): Saccharomyces Cerevisiae W303 Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: Blake borgeson  

LAB HEAD: Andrew Emili

PROVIDER: PXD002327 | Pride | 2015-06-29

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
Sc.fasta Fasta
WAN140125_YEAST_A02.MSGFDB_out Other
WAN140125_YEAST_A02.raw Raw
WAN140125_YEAST_A02.results.pep.xml.xcorr_hit_list_best Pepxml
WAN140125_YEAST_A04.MSGFDB_out Other
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Publications

Macromolecular complexes are essential to conserved biological processes, but their prevalence across animals is unclear. By combining extensive biochemical fractionation with quantitative mass spectrometry, here we directly examined the composition of soluble multiprotein complexes among diverse metazoan models. Using an integrative approach, we generated a draft conservation map consisting of more than one million putative high-confidence co-complex interactions for species with fully sequence  ...[more]

PMID: 26344197

Publication: 1/2