Proteomics

Dataset Information

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Chicken embryo proteome - Quantitative Mass Spectrometry Reveals Partial Translational Regulation for Dosage Compensation in Chicken


ABSTRACT: White Leghorn chicken eggs were incubated for 18 days and dissected. Brain, breast muscle, bursa Fabricii, heart, kidney, liver, lung, ovary, spleen, and testicle tissues were sampled.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Gallus Gallus (chicken)

TISSUE(S): Spleen, Heart, Testis, Ovary, Brain, Lung, Liver, Pectoral Muscle, Bursa Of Fabricius, Kidney

SUBMITTER: Jia Mi  

LAB HEAD: Jonas Bergquist

PROVIDER: PXD002403 | Pride | 2015-07-15

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20140801_LC1_Hans_heart_1160.raw Raw
20140801_LC1_Hans_heart_151.raw Raw
20140801_LC1_Hans_heart_2169.raw Raw
20140801_LC1_Hans_heart_3178.raw Raw
20140801_LC1_Hans_heart_4187.raw Raw
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Publications

Quantitative Mass Spectrometry Reveals Partial Translational Regulation for Dosage Compensation in Chicken.

Uebbing Severin S   Konzer Anne A   Xu Luohao L   Backström Niclas N   Brunström Björn B   Bergquist Jonas J   Ellegren Hans H  

Molecular biology and evolution 20150624 10


There is increasing evidence that dosage compensation is not a ubiquitous feature following sex chromosome evolution, especially not in organisms where females are the heterogametic sex, like in birds. Even when it occurs, compensation can be incomplete and limited to dosage-sensitive genes. However, previous work has mainly studied transcriptional regulation of sex-linked genes, which may not reflect expression at the protein level. Here, we used liquid chromatography-tandem mass spectrometry t  ...[more]