Dataset Information
Proteomics of Secretomes and Exosomes in Melanoma
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA371460
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: 
Javier Munoz
LAB HEAD: Javier Munoz
PROVIDER: PXD002703 | Pride | 2017-06-29
REPOSITORIES: Pride
Dataset's files
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Publications
Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine.
Nature 20170601 7660
Cutaneous melanoma is a type of cancer with an inherent potential for lymph node colonization, which is generally preceded by neolymphangiogenesis. However, sentinel lymph node removal does not necessarily extend the overall survival of patients with melanoma. Moreover, lymphatic vessels collapse and become dysfunctional as melanomas progress. Therefore, it is unclear whether (and how) lymphangiogenesis contributes to visceral metastasis. Soluble and vesicle-associated proteins secreted by tumou ...[more]
