Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Spleen, Heart, Erythrocyte, Blood Platelet, Primary Cell, Blood Cell, Blood Plasma, Leukocyte, Liver, Lung, Neutrophil, Kidney
SUBMITTER: Simon Hauri
LAB HEAD: Johan Malmstrom
PROVIDER: PXD002896 | Pride | 2015-11-23
REPOSITORIES: Pride
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Nature communications 20160106
The plasma proteome is highly dynamic and variable, composed of proteins derived from surrounding tissues and cells. To investigate the complex processes that control the composition of the plasma proteome, we developed a mass spectrometry-based proteomics strategy to infer the origin of proteins detected in murine plasma. The strategy relies on the construction of a comprehensive protein tissue atlas from cells and highly vascularized organs using shotgun mass spectrometry. The protein tissue a ...[more]