Ontology highlight
ABSTRACT:
INSTRUMENT(S): Synapt MS
ORGANISM(S): Bacillus Subtilis Subsp. Subtilis Str. 168
SUBMITTER: Jennifer Stepanek
LAB HEAD: Julia Elisabeth Bandow
PROVIDER: PXD003439 | Pride | 2016-03-14
REPOSITORIES: Pride
Action | DRS | |||
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1001_CHD.raw.zip | Raw | |||
1001_CHD_PLGSoutput.zip | Other | |||
1032_CHD.raw.zip | Raw | |||
1032_CHD_2.raw.zip | Raw | |||
1032_CHD_2_PLGSoutput.zip | Other |
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Stepanek Jennifer J JJ Lukežič Tadeja T Teichert Ines I Petković Hrvoje H Bandow Julia E JE
Biochimica et biophysica acta 20160309 6
Classical tetracyclines targeting the protein biosynthesis machinery are commonly applied in human and veterinary medicine. The development and spread of resistance seriously compromise the successful treatment of bacterial infections. The atypical tetracycline chelocardin holds promise as it retains activity against tetracycline-resistant strains. It has been suggested that chelocardin targets the bacterial membrane, thus differing in mode of action from that of classical tetracyclines. We inve ...[more]