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E. coli EcAmb278 treated with tetracycline

ABSTRACT: Drug profiling exeriment to elucidate protein regulation upon treatment of a multi-drug resistant E.coli strain with tetracycline.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Escherichia Coli

SUBMITTER: Rune Matthiesen

LAB HEAD: Rune Matthiesen

PROVIDER: PXD003641 | Pride | 2017-01-06

REPOSITORIES: Pride

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			Action	DRS
	MS151771QE_Rune_Canica_A1.raw	Raw
	MS151771QE_Rune_Canica_A2.raw	Raw
	MS151771QE_Rune_Canica_A3.raw	Raw
	MS151771QE_Rune_Canica_B1.raw	Raw
	MS151771QE_Rune_Canica_B2.raw	Raw

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Publications

Quantitative proteome analysis of an antibiotic resistant Escherichia coli exposed to tetracycline reveals multiple affected metabolic and peptidoglycan processes.

Jones-Dias Daniela D Carvalho Ana Sofia AS Moura Inês Barata IB Manageiro Vera V Igrejas Gilberto G Caniça Manuela M Matthiesen Rune R

Journal of proteomics 20161230

Tetracyclines are among the most commonly used antibiotics administrated to farm animals for disease treatment and prevention, contributing to the worldwide increase in antibiotic resistance in animal and human pathogens. Although tetracycline mechanisms of resistance are well known, the role of metabolism in bacterial reaction to antibiotic stress is still an important assignment and could contribute to the understanding of tetracycline related stress response. In this study, spectral counts-ba ...[more]

PMID: 28043878

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