Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Unclassified Marseilleviridae
SUBMITTER: Yohann Couté
LAB HEAD: Bruley
PROVIDER: PXD003910 | Pride | 2017-02-09
REPOSITORIES: Pride
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Fabre Elisabeth E Jeudy Sandra S Santini Sébastien S Legendre Matthieu M Trauchessec Mathieu M Couté Yohann Y Claverie Jean-Michel JM Abergel Chantal C
Nature communications 20170421
Acanthamoeba are infected by a remarkable diversity of large dsDNA viruses, the infectious cycles of which have been characterized using genomics, transcriptomics and electron microscopy. Given their gene content and the persistence of the host nucleus throughout their infectious cycle, the Marseilleviridae were initially assumed to fully replicate in the cytoplasm. Unexpectedly, we find that their virions do not incorporate the virus-encoded transcription machinery, making their replication nuc ...[more]