Proteomics

Dataset Information

0

PR1-14A002


ABSTRACT: In quantitative proteomic assay, isobaric tags for relative and absolute quantitation (iTRAQ) combined with 2D LC-MS/MS is emerging as a powerful methodology in the search for disease specific targets and biomarkers using cell lines, tissues, body fluids and so on. In this study, 5325 distinct proteins (unused≥1.3, which means a confidence≥95%) were identified using iTRAQ-based proteomic technology. In total, using a strict cutoff value of 1.5-fold for expressed variation, we found 482 proteins differentially expressed (Pvalue≤0.01) in sample N4 compared to N2. Furthermore, we adopted function annotation analysis of all identified proteins and function enrichment analysis of all differentially expressed proteins to explore more meaningful proteins and pathways.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Colon

SUBMITTER: Jingdong Yin  

LAB HEAD: Jingdong Yin

PROVIDER: PXD004052 | Pride | 2022-03-02

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Pig_CNM_6iTRAQ_f1.wiff Wiff
Pig_CNM_6iTRAQ_f1.wiff.scan Wiff
Pig_CNM_6iTRAQ_f10.wiff Wiff
Pig_CNM_6iTRAQ_f10.wiff.scan Wiff
Pig_CNM_6iTRAQ_f11.wiff Wiff
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