Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos, Q Exactive
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Wolfgang Reiter
LAB HEAD: Gustav Ammerer
PROVIDER: PXD004297 | Pride | 2017-02-01
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 41 |
Romanov Natalie N Hollenstein David Maria DM Janschitz Marion M Ammerer Gustav G Anrather Dorothea D Reiter Wolfgang W
Science signaling 20170307 469
The budding yeast <i>Saccharomyces cerevisiae</i> reacts to increased external osmolarity by modifying many cellular processes. Adaptive signaling relies primarily on the high-osmolarity glycerol (HOG) pathway, which is closely related to the mammalian p38 mitogen-activated protein kinase (MAPK) pathway in core architecture. To identify target proteins of the MAPK Hog1, we designed a mass spectrometry-based high-throughput experiment to measure the impact of Hog1 activation or inhibition on the ...[more]