Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Permanent Cell Line Cell, Hela Cell
DISEASE(S): Disease Free
SUBMITTER: Makoto Kimura
LAB HEAD: Naoko Imamoto
PROVIDER: PXD004655 | Pride | 2017-01-20
REPOSITORIES: Pride
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140815_QE_206_Kimura_01_AC_1.raw | Raw | |||
140815_QE_206_Kimura_02_AC_2.raw | Raw | |||
140815_QE_206_Kimura_03_AC_3.raw | Raw | |||
140815_QE_206_Kimura_04_AC_4.raw | Raw | |||
140815_QE_206_Kimura_05_A13_1.raw | Raw |
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Kimura Makoto M Morinaka Yuriko Y Imai Kenichiro K Kose Shingo S Horton Paul P Imamoto Naoko N
eLife 20170124
Vast numbers of proteins are transported into and out of the nuclei by approximately 20 species of importin-β family nucleocytoplasmic transport receptors. However, the significance of the multiple parallel transport pathways that the receptors constitute is poorly understood because only limited numbers of cargo proteins have been reported. Here, we identified cargo proteins specific to the 12 species of human import receptors with a high-throughput method that employs stable isotope labeling w ...[more]