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Dataset Information

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Ulcerative colitis biopsies analyzed by PCT-SWATH mass spectrometry


ABSTRACT: Ulcerative colitis (UC) is an idiopathic chronic inflammatory disorder of the colonic mucosa with rising incidence. Despite numerous known genetic risk loci environmental factors seem to be crucial in the pathogenesis of this complex disease with suboptimal treatment options. Approaches utilizing methods of systemic biology have been started to use in the analysis of mucosal biopsies in order to get a more comprehensive view of the changes related to the disorder. Our aim was to test the capability of a new mass spectrometry (MS) -based assay (PCT-SWATH mass spectrometry) to characterize host proteomes both in inflamed and non-inflamed colon tissues of an UC patient cohort.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Colon

DISEASE(S): Ulcerative Colitis

SUBMITTER: Petri Kouvonen  

LAB HEAD: Ruedi Aebersold

PROVIDER: PXD004907 | Pride | 2017-06-12

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
PETRIK_L130711_002_SW.zip Other
PETRIK_L130711_003_SW.zip Other
PETRIK_L130711_004_SW.zip Other
PETRIK_L130711_005_SW.zip Other
PETRIK_L130711_006_SW.zip Other
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