Proteomics

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Hadrurus spadix venom - Venom-gland transcriptomics and venom proteomics of the black-back scorpion (Hadrurus spadix) reveal detectability challenges and an unexplored realm of animal toxin diversity


ABSTRACT: We used a combined transcriptomic and proteomic approach to characterize the venom of a male and female of the black-back scorpion (Hadrurus spadix).

INSTRUMENT(S): Q Exactive

ORGANISM(S): Hadrurus Spadix

TISSUE(S): Venom

SUBMITTER: Darin Rokyta  

LAB HEAD: Darin R. Rokyta

PROVIDER: PXD005009 | Pride | 2017-01-30

REPOSITORIES: Pride

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Publications

Venom-gland transcriptomics and venom proteomics of the black-back scorpion (Hadrurus spadix) reveal detectability challenges and an unexplored realm of animal toxin diversity.

Rokyta Darin R DR   Ward Micaiah J MJ  

Toxicon : official journal of the International Society on Toxinology 20170120


The order Scorpiones is one of the most ancient and diverse lineages of venomous animals, having originated approximately 430 million years ago and diversified into 14 extant families. Although partial venom characterizations have been described for numerous scorpion species, we provided the first quantitative transcriptome/proteome comparison for a scorpion species using single-animal approaches. We sequenced the venom-gland transcriptomes of a male and female black-back scorpion (Hadrurus spad  ...[more]

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