Proteomics

Dataset Information

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Discovery of gastric cancer-specific biomarkers by the application of serum proteomics


ABSTRACT: The aims of this study are to compare the proteomes of serum samples from patients with gastric cancers and normal controls, and to develop useful tumor markers of gastric cancer by quantitative proteomic analysis

INSTRUMENT(S): LTQ

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Blood Serum

SUBMITTER: Joon won Lee  

LAB HEAD: Kwang Pyo Kim

PROVIDER: PXD005156 | Pride | 2017-02-08

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
0900325_GC_E1.RAW Raw
0900325_GC_E1.srf Other
0900325_GC_E10.RAW Raw
0900325_GC_E10.srf Other
0900325_GC_E11.RAW Raw
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Publications

Discovery of gastric cancer specific biomarkers by the application of serum proteomics.

Yoo Moon-Won MW   Park Jisook J   Han Hye-Seung HS   Yun Yeo-Min YM   Kang Jeong Won JW   Choi Do-Young DY   Lee Joon Won JW   Jung Jae Hun JH   Lee Kyung-Yung KY   Kim Kwang Pyo KP  

Proteomics 20170301 6


Current diagnostic markers for gastric cancer are not sufficiently specific or sensitive for use in clinical practice. The aims of this study are to compare the proteomes of serum samples from patients with gastric cancers and normal controls, and to develop useful tumor markers of gastric cancer by quantitative proteomic analysis. We identified a total of 388 proteins with a ≤1% FDR and with at least two unique peptides from the sera of each group. Among them, 215, 251, and 260 proteins were id  ...[more]

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