Proteomics

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Tetrasphaera elongata prospers in dynamic oxic/anoxic systems by metabolic pre-adaptation and dismissal of the hierarchical control of anaerobic gene expression


ABSTRACT: The physiological adaptations of the WWTP isolate T. elongata str. LP2 during an oxic/anoxic shift experiment were analyzed by HRMS-proteomics. E. coli was used as reference organism as it shares several metabolic capabilities and is regularly introduced to wastewater treatment plants, but without succeeding there. In contrast to E. coli, T. elongata was able to steadily grow and did not need to activate additional metabolic pathways for anaerobic energy harvest. At the same time, given substrates were exploited far more efficient than by E. coli. Based on the acquired data, we hypothesize that T. elongata shows high metabolic robustness when encountering the WWTP which enables continuous growth to successfully compete in this environment.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Tetrasphaera Elongata Lp2

SUBMITTER: Florian-Alexander Herbst  

LAB HEAD: Per Halkjær Nielsen

PROVIDER: PXD005211 | Pride | 2019-03-18

REPOSITORIES: pride

Dataset's files

Source:
Action DRS
FAH_Ec_3H_1.raw Raw
FAH_Ec_3H_2.raw Raw
FAH_Ec_3H_3.raw Raw
FAH_Ec_3H_4.raw Raw
FAH_Ec_Ox_1.raw Raw
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