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Colistin resistance in Acinetobacter baumannii MDR-ZJ06 revealed by a multiomics approach

ABSTRACT: To explore how multiple drug-resistant A. baumannii response to colistin resistance, we compared the genomic, transcriptional and proteomic profile of A. baumannii MDR-ZJ06 to that of induced colistin resistant strain ZJ06-200P5-1.

OTHER RELATED OMICS DATASETS IN: PRJNA341912

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Acinetobacter Baumannii

TISSUE(S): Cell Culture

SUBMITTER: Xiaoting Hua

LAB HEAD: Yunsong Yu

PROVIDER: PXD005265 | Pride | 2017-03-15

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	P12206_1.dat	Other
	P12206_1.dat-pride.pride.mgf.gz	Mgf
	P12206_1.dat-pride.pride.mztab.gz	Mztab
	P12206_1.dat-pride.xml.gz	Xml
	P12206_1.raw	Raw

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Publications

Colistin Resistance in Acinetobacter baumannii MDR-ZJ06 Revealed by a Multiomics Approach.

Hua Xiaoting X Liu Lilin L Fang Youhong Y Shi Qiucheng Q Li Xi X Chen Qiong Q Shi Keren K Jiang Yan Y Zhou Hua H Yu Yunsong Y

Frontiers in cellular and infection microbiology 20170222

Acinetobacter baumannii has emerged as an important opportunistic pathogen due to its ability to acquire resistance to most currently available antibiotics. Colistin is often considered as the last line of therapy for infections caused by multidrug-resistant A. baumannii (MDRAB). However, colistin-resistant A. baumannii strain has recently been reported. To explore how multiple drug-resistant A. baumannii responded to colistin resistance, we compared the genomic, tran ...[more]

PMID: 28275586

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