Proteomics

Dataset Information

0

Defining the Akt1 interactome and delineating alterations in its composition as a function of cell cycle progression.


ABSTRACT: Akt1 expressing Hek 293 cells were SILAC labeled to capture dynamic changes in Akt1 interactome as the cell cycle progresses from G0 to G1S and then G2 phase. This will help in understanding how Akt1 extends its regulatory effect upon cell cycle progression.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Shweta Duggal  

LAB HEAD: Dr. Kanury V.S. Rao

PROVIDER: PXD005557 | Pride | 2017-01-16

REPOSITORIES: Pride

Dataset's files

Source:
altmetric image

Publications

Defining the Akt1 interactome data and delineating alterations in its composition as a function of cell cycle progression.

Duggal Shweta S   Jailkhani Noor N   Midha Mukul Kumar MK   Rao Kanury V S KV   Kumar Ajay A  

Data in brief 20170212


Akt1 is a multi-functional protein implicated in key cellular processes including regulation of proliferation, survival, metabolism and protein synthesis. Its functional diversity results through interactions with other proteins which change with changing context. This study was designed to capture proteins, which interact with Akt1 as the cell cycle progresses from G0 to G1S and then G2 phase. Such an insight might help us understand the role of Akt1 in cell cycle, which as of now is not well e  ...[more]

Similar Datasets

2017-03-02 | PXD005976 | Pride
2017-09-14 | PXD007708 | Pride
2021-09-01 | PXD022061 | Pride
2019-04-30 | PXD012548 | Pride
2009-08-21 | GSE17421 | GEO
2024-08-23 | PXD039028 | Pride
2008-06-16 | E-GEOD-9484 | biostudies-arrayexpress
2009-08-21 | E-GEOD-17421 | biostudies-arrayexpress
2008-03-06 | E-MEXP-1412 | biostudies-arrayexpress
2019-04-24 | GSE130187 | GEO