Dataset Information

Analysis of gradient purified immune suppressive particles from L. heterotoma NY parasitoid wasp

ABSTRACT: The composition and biotic nature of wasp VLPs has remained uncharacterized. VLP proteomics have contributed to a new understanding of their unusual organelle nature and mechanism of action in suppressing host defense responses.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Leptopilina

SUBMITTER: Mary Heavner

LAB HEAD: Shubha Govind

PROVIDER: PXD005639 | Pride | 2017-09-13

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	GG_Gel02_B01.RAW	Raw
	GG_Gel02_B01_10ppm0.6Da.msf.mzid.gz	Mzid
	GG_Gel02_B01_10ppm0.6Da.msf.mzid_GG_Gel02_B01_10ppm0.6Da.msf.MGF	Mzid
	GG_Gel02_B01_10ppm0.6Da.msf.mzid_GG_Gel02_B01_10ppm0.6Da.msf.pride.mgf.gz	Mzid
	GG_Gel02_B01_10ppm0.6Da.msf.pride.mztab.gz	Mztab

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Publications

Novel Organelles with Elements of Bacterial and Eukaryotic Secretion Systems Weaponize Parasites of Drosophila.

Heavner Mary Ellen ME Ramroop Johnny J Gueguen Gwenaelle G Ramrattan Girish G Dolios Georgia G Scarpati Michael M Kwiat Jonathan J Bhattacharya Sharmila S Wang Rong R Singh Shaneen S Govind Shubha S

Current biology : CB 20170907 18

The evolutionary success of parasitoid wasps, a highly diverse group of insects widely used in biocontrol, depends on a variety of life history strategies in conflict with those of their hosts [1]. Drosophila melanogaster is a natural host of parasitic wasps of the genus Leptopilina. Attack by L. boulardi (Lb), a specialist wasp to flies of the melanogaster group, activates NF-κB-mediated humoral and cellular immunity. Inflammatory blood cells mobilize and encapsulate Lb eggs and embryos [2-5]. ...[more]

PMID: 28889977

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