Proteomics

Dataset Information

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The interactome of multiprotein bridging factor 1 in Beauveria bassiana


ABSTRACT: Beauveria basiana is a well-known filamentous entomopathogenic fungus. Oxidation tolerance is an important determinant to fungal pathogenicity and biocontrol potential. B. bassiana transcriptional co-activator multiprotein bridging factor 1 (BbMBF1) contributes to fungal resistance to the oxidative stress. The interactome of BbMBF1 was revealed by the qualitative proteomic analysis integrated with the immuno-precipitation. This study is sought to unveil the comprehensive protein interaction of BbMBF1 and isolate the BbMBF1-mediated transcription factor under oxidative stress.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Beauveria Bassiana (strain Arsef 2860) (white Muscardine Disease Fungus) (tritirachium Shiotae)

TISSUE(S): Mycelium

SUBMITTER: Sheng-hua Ying  

LAB HEAD: Sheng-Hua Ying

PROVIDER: PXD005660 | Pride | 2017-09-11

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
CK_1.raw Raw
CK_2.raw Raw
MBF1interactome.dat Other
MBF1interactome.mgf Mgf
MD_1.raw Raw
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Publications

Interactome analysis of transcriptional coactivator multiprotein bridging factor 1 unveils a yeast AP-1-like transcription factor involved in oxidation tolerance of mycopathogen Beauveria bassiana.

Chu Xin-Ling XL   Dong Wei-Xia WX   Ding Jin-Li JL   Feng Ming-Guang MG   Ying Sheng-Hua SH  

Current genetics 20170904 1


Oxidation tolerance is an important determinant to predict the virulence and biocontrol potential of Beauveria bassiana, a well-known entomopathogenic fungus. As a transcriptional coactivator, multiprotein bridging factor 1 mediates the activity of transcription factor in diverse physiological processes, and its homolog in B. bassiana (BbMBF1) contributes to fungal oxidation tolerance. In this study, the BbMBF1-interactomes under oxidative stress and normal growth condition were deciphered by ma  ...[more]

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