Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Trypanosoma Brucei
SUBMITTER: Friedel Drepper
LAB HEAD: Prof. Dr. Bettina Warscheid
PROVIDER: PXD005730 | Pride | 2017-06-14
REPOSITORIES: Pride
Action | DRS | |||
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ELITE-RSLC016308.raw | Raw | |||
ELITE-RSLC016309.raw | Raw | |||
ELITE-RSLC016310.raw | Raw | |||
ELITE-RSLC016311.raw | Raw | |||
ELITE-RSLC016312.raw | Raw |
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Nature communications 20170509
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analysing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting our understanding of organellar biogenesis and function. Here we introduce a method that enables charting an organelle's importome. The approach relies on inducible RNAi-mediated knockdown of an essenti ...[more]