Proteomics

Dataset Information

0

Phosphorylation of OSBL8 protein in interphase vs mitotic human cells


ABSTRACT: Phosphorylation of OSBL8 human protein was compared in interphase vs mitotic Hela cells with a new software developed in-house, Msviz, a graphical software tool developed for in-depth manual validation and quantitation of post-translational modifications.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Cell Culture

SUBMITTER: Patrice Waridel  

LAB HEAD: Manfredo Quadroni

PROVIDER: PXD006254 | Pride | 2017-07-03

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
FLAG-I_7557-B.dat Other
FLAG-I_7557-B.mgf Mgf
FLAG-I_7557-B.mzML Mzml
FLAG-I_7557-B.mzid Mzid
FLAG-I_7557-B.raw Raw
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Publications

MsViz: A Graphical Software Tool for In-Depth Manual Validation and Quantitation of Post-translational Modifications.

Martín-Campos Trinidad T   Mylonas Roman R   Masselot Alexandre A   Waridel Patrice P   Petricevic Tanja T   Xenarios Ioannis I   Quadroni Manfredo M  

Journal of proteome research 20170706 8


Mass spectrometry (MS) has become the tool of choice for the large scale identification and quantitation of proteins and their post-translational modifications (PTMs). This development has been enabled by powerful software packages for the automated analysis of MS data. While data on PTMs of thousands of proteins can nowadays be readily obtained, fully deciphering the complexity and combinatorics of modification patterns even on a single protein often remains challenging. Moreover, functional in  ...[more]

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