Dataset Information

Comparison of extracellular matrix in prostate tissue samples and in cultures of primary fibroblasts from prostate cancer patients

ABSTRACT: xtracellular matrix from prostate tissue samples and from cultures of primary fibroblasts of the same samples from individuals was analysed by mass spectrometry.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Prostate Gland, Cell Culture, Fibroblast

SUBMITTER: Pekka Rappu

LAB HEAD: Jyrki Heino

PROVIDER: PXD006562 | Pride | 2018-03-13

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	130920_PekkaR_S17Rup_insoluble_undil.mgf	Mgf
	130920_PekkaR_S17Rup_insoluble_undil.msf	Msf
	130920_PekkaR_S17Rup_insoluble_undil.raw	Raw
	131015_PekkaR_S17-INS-old.mgf	Mgf
	131015_PekkaR_S17-INS-old.msf	Msf

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Publications

The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis.

Ojalill Marjaana M Rappu Pekka P Siljamäki Elina E Taimen Pekka P Boström Peter P Heino Jyrki J

The Prostate 20180309 8

<h4>Background</h4>The composition and organization of extracellular matrix (ECM) are important regulators of cell behavior. In particular in the prostate, this central role of the ECM is further stressed by the fact that several potential markers of prostate stem cells are matrix receptors.<h4>Methods</h4>We established 12 fibroblastic cell lines from cancerous and non-cancerous areas of six prostates and allowed the cells to produce ECM under cell culture conditions. We also performed a proteo ...[more]

PMID: 29520855

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