Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): B Cell, T Cell, Cell Culture
DISEASE(S): Cardiovascular System Disease,Colon Cancer,Inflammation
SUBMITTER: Christina Woo
LAB HEAD: Christina May Woo
PROVIDER: PXD007094 | Pride | 2019-01-25
REPOSITORIES: Pride
Items per page: 1 - 5 of 58 |
Journal of the American Chemical Society 20180315 12
Many therapeutics elicit cell-type specific polypharmacology that is executed by a network of molecular recognition events between a small molecule and the whole proteome. However, measurement of the structures that underpin the molecular associations between the proteome and even common therapeutics, such as the nonsteroidal anti-inflammatory drugs (NSAIDs), is limited by the inability to map the small molecule interactome. To address this gap, we developed a platform termed small molecule inte ...[more]