Proteomics

Dataset Information

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Proteome Turnover in Bloodstream and Procyclic form Trypanosoma brucei Measured by Quantitative Proteomics


ABSTRACT: Cellular proteins vary significantly in both abundance and turnover rates. These parameters depend upon their rates of synthesis and degradation and it is useful to have look-up data on protein turnover rates when, for example, designing genetic knock-down experiments or assessing the potential usefulness of covalent enzyme inhibitors. Little is known about the nature and regulation of protein turnover in Trypanosoma brucei, the etiological agent human and animal African trypanosomiasis.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Trypanosoma Brucei

SUBMITTER: Michele Tinti  

LAB HEAD: Sir Michael Ferguson

PROVIDER: PXD007115 | Pride | 2019-09-17

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
BSF_MAXQUANT_TXT_FOLDER.zip Other
LG-1hr-A1.raw Raw
LG-1hr-A10.raw Raw
LG-1hr-A2.raw Raw
LG-1hr-A3.raw Raw
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Publications

Proteome turnover in the bloodstream and procyclic forms of <i>Trypanosoma brucei</i> measured by quantitative proteomics.

Tinti Michele M   Güther Maria Lucia S MLS   Crozier Thomas W M TWM   Lamond Angus I AI   Ferguson Michael A J MAJ  

Wellcome open research 20191009


<b>Background</b>: Cellular proteins vary significantly in both abundance and turnover rates. These parameters depend upon their rates of synthesis and degradation and it is useful to have access to data on protein turnover rates when, for example, designing genetic knock-down experiments or assessing the potential usefulness of covalent enzyme inhibitors. Little is known about the nature and regulation of protein turnover in <i>Trypanosoma brucei</i>, the etiological agent of human and animal A  ...[more]

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