Dataset Information
Neuropilin-2 (NRP2) is the receptor for human cytomegalovirus (HCMV) pentameric complex and is responsible for HCMV infection
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Alexander Leitner
LAB HEAD: Claudio Ciferri
PROVIDER: PXD007185 | Pride | 2018-07-26
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Results_summary_PRIDE.xlsx | Xlsx | |||
| aleitner_C1703_349.raw | Raw | |||
| aleitner_C1703_350.raw | Raw | |||
| aleitner_C1703_351.raw | Raw | |||
| aleitner_C1703_352.raw | Raw |
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Publications
An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor.
Cell 20180726 5
Characterizing cell surface receptors mediating viral infection is critical for understanding viral tropism and developing antiviral therapies. Nevertheless, due to challenges associated with detecting protein interactions on the cell surface, the host receptors of many human pathogens remain unknown. Here, we build a library consisting of most single transmembrane human receptors and implement a workflow for unbiased and high-sensitivity detection of receptor-ligand interactions. We apply this ...[more]
