Dataset Information

Human hair shaft LC-MS/MS - Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins

ABSTRACT: The aim of this work was to define the hair proteome after extractions with both detergent and detergent-free buffers using highly sensitive proteomics technologies based on mass spectrometry.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hair Shaft

SUBMITTER: Sunil Adav

LAB HEAD: Prof. Sze S K

PROVIDER: PXD007224 | Pride | 2018-01-30

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	160219_Sunil_KAP_LKC_SDSII_A1.raw	Raw
	160219_Sunil_KAP_LKC_SDSII_A2.raw	Raw
	160219_Sunil_KAP_LKC_SDSII_A3.raw	Raw
	160219_Sunil_KAP_LKC_SDSII_B1.raw	Raw
	160219_Sunil_KAP_LKC_SDSII_B2.raw	Raw

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Publications

Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins.

Adav Sunil S SS Subbaiaih Roopa S RS Kerk Swat Kim SK Lee Amelia Yilin AY Lai Hui Ying HY Ng Kee Woei KW Sze Siu Kwan SK Schmidtchen Artur A

Scientific reports 20180125 1

Human hair is laminar-fibrous tissue and an evolutionarily old keratinization product of follicle trichocytes. Studies on the hair proteome can give new insights into hair function and lead to the development of novel biomarkers for hair in health and disease. Human hair proteins were extracted by detergent and detergent-free techniques. We adopted a shotgun proteomics approach, which demonstrated a large extractability and variety of hair proteins after detergent extraction. We found an enrichm ...[more]

PMID: 29371649

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