Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Tongue
DISEASE(S): Oral Squamous Cell Carcinoma
SUBMITTER: Adriana Franco Paes Leme
LAB HEAD: Adriana Franco Paes Leme Squina
PROVIDER: PXD007232 | Pride | 2018-09-10
REPOSITORIES: Pride
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Carnielli Carolina Moretto CM Macedo Carolina Carneiro Soares CCS De Rossi Tatiane T Granato Daniela Campos DC Rivera César C Domingues Romênia Ramos RR Pauletti Bianca Alves BA Yokoo Sami S Heberle Henry H Busso-Lopes Ariane Fidelis AF Cervigne Nilva Karla NK Sawazaki-Calone Iris I Meirelles Gabriela Vaz GV Marchi Fábio Albuquerque FA Telles Guilherme Pimentel GP Minghim Rosane R Ribeiro Ana Carolina Prado ACP Brandão Thaís Bianca TB de Castro Gilberto G González-Arriagada Wilfredo Alejandro WA Gomes Alexandre A Penteado Fabio F Santos-Silva Alan Roger AR Lopes Márcio Ajudarte MA Rodrigues Priscila Campioni PC Sundquist Elias E Salo Tuula T da Silva Sabrina Daniela SD Alaoui-Jamali Moulay A MA Graner Edgard E Fox Jay W JW Coletta Ricardo Della RD Paes Leme Adriana Franco AF
Nature communications 20180905 1
Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological and molecular characteristics limiting the standard tumor-node-metastasis prognosis classification. Therefore, defining biological signatures that allow assessing the prognostic outcomes for OSCC patients would be of great clinical significance. Using histopathology-guided discovery proteomics, we analyze neoplastic islands and stroma from the invasive tumor front (ITF) and inner tumor to identify differen ...[more]