Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Trypanosoma Brucei
SUBMITTER: Michele Tinti
LAB HEAD: Michael Ferguson
PROVIDER: PXD007236 | Pride | 2017-09-20
REPOSITORIES: pride
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Jinnelov Anders A Ali Liaqat L Tinti Michele M Güther Maria Lucia S MLS Ferguson Michael A J MAJ
The Journal of biological chemistry 20170919 49
<i>Trypanosoma brucei</i> causes African trypanosomiasis and contains three full-length oligosaccharyltransferase (OST) genes; two of which, <i>Tb</i>STT3A and <i>Tb</i>STT3B, are expressed in the bloodstream form of the parasite. These OSTs have different peptide acceptor and lipid-linked oligosaccharide donor specificities, and trypanosomes do not follow many of the canonical rules developed for other eukaryotic <i>N</i>-glycosylation pathways, raising questions as to the basic architecture an ...[more]