Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Mycoplasma Pneumoniae (strain Atcc 29342 / M129)
SUBMITTER: Eva Yus
LAB HEAD: Luis Serrano
PROVIDER: PXD007566 | Pride | 2019-11-12
REPOSITORIES: Pride
Action | DRS | |||
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131018_S_EYLS_01_01.msf | Msf | |||
131018_S_EYLS_01_01.raw | Raw | |||
131018_S_EYLS_01_02.msf | Msf | |||
131018_S_EYLS_01_02.raw | Raw | |||
131018_S_EYLS_02_01.msf | Msf |
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Cell systems 20190821 2
Here, we determined the relative importance of different transcriptional mechanisms in the genome-reduced bacterium Mycoplasma pneumoniae, by employing an array of experimental techniques under multiple genetic and environmental perturbations. Of the 143 genes tested (21% of the bacterium's annotated proteins), only 55% showed an altered phenotype, highlighting the robustness of biological systems. We identified nine transcription factors (TFs) and their targets, representing 43% of the genome, ...[more]